Looks like most stock market gains are made when you’re asleep. So yeah just check it. Bespoke Investment Group The biggest increases for the S&P 500 this year have been generated between 10 a.m. and 11 a.m. ET, but the longer-term data are even more interesting.Another chart, based on hourly price patterns since the bull market began on March 9, 2009, is even more interesting: Bespoke Investment GroupThe light blue line represents the prior day’s close (4 p.m.) until 10 a.m. ET. According to Bespoke analyst George Pearkes, the overnight period from the prior market close until 10 a.m. ET offers the best longer-term performance. So there are some tips in this study: examples of S&P 500 ETFs you can use to try and take advantage of this trading pattern include the Vanguard S&P 500 Index ETF VFV the SPDR S&P 500 Index ETF Trust SPY and the iShares S&P 500 Index ETF IVV. Pearkes said company, economic and other news greatly affects stock prices even when the U.S. market is closed.